Lipid layers on polyelectrolyte multilayer supports

Polyelectrolyte multilayer-cushioned fluid lipid bilayers: a parachute model.

Lipid bilayer membranes supported on polyelectrolyte multilayers are widely used as a new biomembrane model that connects biological and artificial materials since these ultrathin polyelectrolyte supports may mimic the role of the extracellular matrix and cell skeleton in living systems. Polyelectrolyte multilayers were fabricated by a layer-by-layer self-assembly technique. A quartz crystal mi...

Polyelectrolyte Multilayer Capsule: a Review

Polyelectrolyte Adsorption and Multilayer Formation

In this chapter, we review our recent theoretical work on the formation of polyelectrolyte multilayers. The first layer is obtained by polyelectrolyte adsorption on a surface with an opposite charge. The adsorbed polyelectrolyte charge is sufficient to invert the charge of the surface. Each subsequent layer is bound to the previous one by the formation of a polyelectrolyte complex. Using a Deby...

Elasticity of polyelectrolyte multilayer microcapsules.

We present a novel approach to probe elastic properties of polyelectrolyte multilayer microcapsules. The method is based on measurements of the capsule load-deformation curves with the atomic force microscope. The experiment suggests that at low applied load deformations of the capsule shell are elastic. Using elastic theory of membranes we relate force, deformation, elastic moduli, and charact...

Osteoconductive protamine-based polyelectrolyte multilayer functionalized surfaces.

The integration of orthopedic implants with host bone presents a major challenge in joint arthroplasty, spinal fusion and tumor reconstruction. The cellular microenvironment can be programmed via implant surface functionalization allowing direct modulation of osteoblast adhesion, proliferation, and differentiation at the implant--bone interface. The development of layer-by-layer assembled polye...